Banner, David,Guba, Wolfgang,Hilpert, Hans,Mauser, Harald,Mayweg, Alexander V.,Narquizian, Robert,Pinard, Emmanuel,Power, Eoin,Rogers-Evans, Mark,Woltering, Thomas,Wostl, Wolfgang
申请号：
AU2013202820
公开号：
AU2013202820A1
申请日:
2013.04.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2013202820A120130502.pdf#####2-AMINO-5, 5-DIFLUORO-5, 6-DIHYDRO-4H-OXAZINES AS BACE 1 AND/OR BACE 2 INHIBITORS 5 Abstract The present invention relates to 2-Amino-5, 5-difluoro-5, 6-dihydro-4H[1,3]oxazin-4-yl)-phenyl]-amide derivatives of formula (I) having BACE1 and/or BACE2 10 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
