Raymond Michael Dimphena Verhaert,Pieter Victor Schut,Sharief Barends,Maurice Wilhelmus van der Heijden
申请号：
US15720428
公开号：
US20180044677A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention describes mRNA usage improving and/or translation-enhancing nucleic acid sequences, nucleic acid constructs comprising such sequences, and host cells comprising such nucleic acid constructs. The invention further pertains to a method for expressing a protein of interest in a cell or organismusing such nucleic acid sequences, as well as their uses for increasing integration of such nucleic acid construct into a genome, for enhancing mRNA usage and/or translation of a recombinantly expressed polypeptide, and for increasing the number of transformants upon transformation of a cell with such nucleic acid construct.
