Cindy A. Sprecher,Scott R. Presnell,Zeren Gao,Theodore E. Whitmore,Joseph L. Kuijper,Mark F. Maurer
申请号：
US13090316
公开号：
US08309692B2
申请日:
2011.04.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
