The present invention provides a method for producing acomposition containing 2-acyl-lysophosphatidylserine, including (a) astep of obtaining a composition containing phosphatidylserine byallowing phospholipase D to act on a raw material containingphosphatidylcholine in the presence of serine and (b) a step of obtaininga composition containing 2-acyl-lysophosphatidylserine by allowingphospholipase A1 to act on the composition containingphosphatidylserine in the presence of one or more additives selectedfrom the group consisting of the following (I), (II), and (III), in which(I) one or more salts selected from the group consisting of sulfate salts,phosphate salts, nitrate salts, citrate salts, and tartarate salts ofmonovalent cations, (II) a gum, and (III) an emulsifier.
