ALFONSO POZZAN,GORDANA BABIC ATALLAH,LUCAL FRANCESCO RAVEGLIA,RICCARDO ZANALETTI,WEI CHEN,ZHAOZHONG J. JIA
申请号:
BR112017025986
公开号:
BR112017025986A2
申请日:
2016.06.02
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.