HEYES, James,HOLLAND, Richard J.,MARTIN, Alan D.,WOOD, Mark
申请号:
EP17781679
公开号:
EP3443092A4
申请日:
2017.04.11
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic nucleic acids to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).