Method for using BOC/CDO to modulate hedgehog signaling

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专利权人:

Curis, Inc.;GENENTECH, INC.; INC.;GENENTECH

发明人:

De Sauvage, Frederic J.,Tian, Hua

申请号：

AU2007243946

公开号：

AU2007243946B2

申请日:

2007.01.22

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention provides for a method of using BOC/CDO hedgehog antagonists to inhibit hedgehog signaling, as well as treating and diagnosing disorders relating to hedgehog signaling or overexpression of hedgehog, including cancer, cell proliferative disorders, and angiogenesis, neurological disorders, as well as other conditions affected by hedgehog signaling such as hair growth, neural stem cell differentiation, chondrogenesis and osteogenesis, lung surfactant production, formation of lamellated bodies in lung cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/