MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人:
BADLEY, ANDREW D.
申请号：
CA3053247
公开号：
CA3053247A1
申请日:
2018.02.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
This document provides antibodies against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) short, and more particularly to humanized TRAILshort antibodies that can neutralize TRAILshort. For example, materials and methods for using one or more humanized TRAILshort antibodies to induce apoptosis (e.g., via TRAIL mediated cell death, natural killer (NK) cytotoxicity, and/or CD8+ T cell killing) are provided.
