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METHOD FOR INDUCING IMMUNE STIMULATION USING NON-PROLIFERATIVE ALLOGENEIC LEUKOCYTES
专利权人:
CANADIAN BLOOD SERVICES
发明人:
SCOTT, MARK D.,WANG, DUNCHENG,TOYOFUKU, WENDY M.
申请号:
EP13817038
公开号:
EP2872150A4
申请日:
2013.07.12
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
This invention relates to cellular-based therapies for increasing the level of regulatory T cells (Treg) and/or decreasing the level of pro-inflammatory T cells (Th17) to induce anergy or immune tolerance. To provide these therapeutic effects, two allogeneic leukocyte populations are contacted (in vivo, in vitro or ex vivo) and one of these leukocyte population is modified to bear on its surface a low-immunogenic biocompatible polymer so as to prevent pro-inflammatory allo-recognition. Cellular-based preparations and processes for achieving cellular therapy are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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