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Local vascular delivery of adenosine A2A receptor agonists to reduce myocardial injury
专利权人:
コーディス・コーポレイション
发明人:
ファロティコ・ロバート,パーカー・セオドア・エル
申请号:
JP2013539901
公开号:
JP6042342B2
申请日:
2011.11.09
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
A stent or other implantable medical device for the local delivery of a selective adenosine receptor agonist may be utilized to reduce myocardial injury following an acute myocardial infarction. As soon as possible following an acute myocardial infarction a stent or other suitable device comprising and capable of delivering a selective adenosine receptor agonist is positioned in the blood vessel with the occlusion responsible for causing the infarct. Once in position , the stent or other intraluminal device is deployed to remove the occlusion and reestablish blood flow to the specific area, region or tissue volume of the heart. Over a given period of time the selective adenosine receptor agonist elutes from the stent or other device into the downstream coronary blood flow into the hypoxic cardiac tissue for a time sufficient to reduce the level of myocardial injury.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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