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PARTICULES DE CORTICOSTEROIDES ET LEUR PROCEDE DE PRODUCTION
专利权人:
MAP PHARMACEUTICALS; INC.
发明人:
WU, LIBO,WATANABE, WIWIK,ZHANG, JIAN
申请号:
CA2812263
公开号:
CA2812263A1
申请日:
2011.09.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A new particle morphology of glucocorticosteroids is described. The forms have a particle morphology that is particularly well suited for use in an inhaled corticosteroid drug suspension formulation for delivery from a next generation nebulizer device. Use of the new glucocorticosteroid particles enables enhanced drug delivery efficiency and increased residence time of the delivered drug in the lungs. New methods for producing glucocorticosteroid particles having these specific particle morphologies are also described. The methods provide a simplified, reproducible and scalable particle formation process that can produce glucocorticosteroid particles having a narrow particle size and shape distribution, a low surface energy, a low aspect ratio, uniform particle morphology and a reduced specific surface area.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
tomohiko hashiba
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