An irradiation device for insertion into an orifice of the body for providing photodynamic therapy comprises: a housing 1, 21, 31, 51, 61, 71 adapted to be fully inserted and secured in the orifice, the housing 1, 21, 31, 51, 61, 71 enclosing an LED lamp system 5, 25, 35, 45, 54, 62, 72 and a power source 41, 68, 78 for powering the LED lamp system 5, 25, 35, 45, 54, 62, 72 and the housing 1, 21, 31, 51, 61, 71 comprising a treatment surface 2, 22, 32, 63, 73 with the LED system 5, 25, 35, 45, 54, 62, 72 being arranged to, when the device is in operation, emit light at a light intensity in the range of 1-50 mW/cm 2 form the treatment surface 2, 22, 32, 63, 73, wherein the treatment surface 2, 22, 32, 63, 73 is at least partially transparent to said light and has a size and/or shape adapted for complementary fit with a treatment area within the orifice such that, when the device is in operation, the treatment area is illuminated by said light and wherein the device is independently operational while located in the orifice.
