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TEST D'ACTIVITE BIOLOGIQUE DE CELLULE DENDRITIQUE
专利权人:
MEDIGENE IMMUNOTHERAPIES GMBH
发明人:
SCHENDEL, DOLORES,ECKL, JUDITH,GEIGER, CHRISTIANE,ROMER, ISABEL
申请号:
CA3074612
公开号:
CA3074612A1
申请日:
2017.09.05
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to a method for determining the potency of DCs, comprising the steps: stimulating dendritic cells by incubation with soluble CD40L and TLR7/8 agonist, measuring the secretion of the marker proteins IL-10 and IL-12 from the stimulated dendritic cells. Thereby it can be determined whether the dendritic cell have a high capability to activate T-cells and Natural Killer (NK) cells. The invention also encompasses a method for stimulating dendritic cells comprising the step of stimulating the dendritic cells with soluble CD40L and TLR7/8 agonist.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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