MITCHELL, SCOTT A.,CURRIE, KEVIN S.,BLOMGREN, PETER A.,KROPF, JEFFREY E.,LEE, SEUNG H.,XU, JIANJUN,STAFFORD, DOUGLAS G.,HARDING, JAMES P.,BARBOSA, JR., ANTONIO J.,ZHAO, ZHONGDONG,ARMISTEAD, DAVID, M.
申请号:
HK15112867.8
公开号:
HK1211939A
申请日:
2015.12.30
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Certain imidazopyrazines and pharmaceutical compositions thereof are provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.