PROBLEM TO BE SOLVED: To provide a drug delivery composition for administering a biologically active molecule, such as low molecules, peptides, and nucleic acids, to a subject and methods for the preparation of said composition.SOLUTION: The present invention is directed to a drug delivery composition comprising a biologically active molecule encapsulated in a self-assembled nanostructure that comprises surfactant peptides, selected from the group consisting of a plurality of specific sequence numbers, wherein the biologically active molecule is delivered to the gastrointestinal tract or across the blood brain barrier of a subject.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】低分子,ペプチド及び核酸等の生物活性分子を被験体に投与するための薬物送達組成物及びその調製方法の提供。【解決手段】複数の特定の配列番号を有する群より選択される界面活性剤ペプチドを含有する自己組織化ナノ構造中に封入された生物活性分子を含む薬物送達組成物及び前記組成物の調製方法。前記生物活性分子は、被験者の胃腸管に、または血液脳関門を横切って送達される。【選択図】図1
