Novartis AG;The Trustees of The University of Pennsylvania
发明人:
申请号：
EP20160131.7
公开号：
EP3722316A1
申请日:
2015.07.21
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention provides compositions and methods for treating diseases associated with expression of CD33. The invention also relates to chimeric antigen receptor (CAR) specific to CD33, vectors encoding the same, and recombinant T cells comprising the CD33 CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a CD33 binding domain.
