process for the in vitro expansion of antigen-specific t cells, expanded autologous or allogeneic t-cell product, pharmaceutical composition, and method of treatment of a patient, and uses of an engineered cell line, mixed pulsed dendritic cells antigen-peptide, t-apcs pulsed with antigen-peptide / peptide mixtures, and antigen-peptide mixtures with pbmcs
ANN M. LEEN,CLIONA M. ROONEY,JUAN F. VERA,MINHTRAN V. NGO,RAINER LUDWIG KNAUS
申请号：
BR112014014591
公开号：
BR112014014591A8
申请日:
2012.04.23
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present disclosure relates to a novel process for expanding T cells, such as autologous T cells, cell populations therefrom, pharmaceutical compositions comprising the said cell populations and use of the cells and compositions for treatment, particular the treatment or prophylaxis of virus infection and/or cancer, for example in immune compromised or immune competent human patients.
