A biopsy system includes an endoscope which includes an insertion portion having a channel, and a bendable portion provided in a distal end portion of the insertion portion and capable of being operated to be bent; a needle tube which includes a distal end region, and a proximal end region having a higher bending rigidity than the bending rigidity of the distal end region; a sheath which is capable of being inserted into the channel and inserted through by the needle tube; an attachment adapter which is provided on a proximal end side of the sheath and is capable of being mounted at the endoscope; and a connection member which connects the distal end region and the proximal end region, wherein in a state where the sheath is inserted through the channel and the attachment adapter is mounted at the endoscope, the connection member is capable of moving within only a range of the insertion portion more proximal than a proximal end of the bendable portion and more distal than a proximal end of a follow-bending region which is capable of being passively bent along a greater curvature of the stomach when a distal end of the insertion portion is positioned at a position of the duodenal bulb.