The present invention relates to chemical compounds and the therapeutic use thereof, in particular for improving muscular quality in mammals. More particularly, the invention enables improvement of muscular quality in sarcopenic mammals and treatment and/or prevention of sarcopenia and, in particular, sarcopenic obesity and the associated complications and/or pathologies thereof, such as loss of strength, muscle mass, performance and of physical and movement capacity. The invention also enables improvement of muscle quality in obese mammals and the treatment and/or prevention of obesity and associated complications and/or pathologies, advantageously type 2 diabetes and metabolic syndrome.