In one aspect, this invention relates to a composition of matter useful for treating homeostatic malfunction and subsequent resulting conditions. In another aspect, this invention relates to the disclosure of unexpected synergies created by certain mixtures that increase the nature and function of those mixtures over any of the ingredients alone. In another aspect, this invention relates to a method for treating homeostatic instability conditions. In yet another aspect, this invention relates to formulating a synergistic agent to return mammalian systems to normal set point conditions—;i.e., homeostasis—;across a surprising number of different pain, inflammation and other expressions of non-homeostasis.