Disclosed are topical skin care compositions and methods for their use that include a chemically compatible combination of palmitoyl tetrapeptide 7 and Euterpe oleracea fruit extract or Terminalia ferdinandiana fruit extract, and a dermatologically acceptable vehicle comprising water, glycerin, butylene glycol, propylene glycol, and disodium EDTA, wherein the topical skin care composition is formulated for topical application to skin.