METHODS FOR IN VITRO PRODUCTION OF PLATELETS AND COMPOSITIONS AND USES THEREOF

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专利权人:

Jeffrey Thomas Loh

发明人:

Jeffrey Thomas Loh

申请号：

US15553530

公开号：

US20180237797A1

申请日:

2016.03.29

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention encompasses methods for generating mutant janus kinase 2 (JAK-2), mutant calreticulin (CALR), or thrombopoietin receptor (MPL) modified megakaryocytes (modified MKs) expressing a mutant Janus kinase 2 peptide, a mutant calreticulin peptide, and/or a mutant thrombopoietin receptor peptide, JAK2-, CALR-, and/or MPL-modified platelets as a composition of matter, and methods for using the generated JAK2-, CALR-, and/or MPL-modified platelets.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/