A syringe assembly includes a syringe barrel having a tubular body that bounds a compartment extending between a proximal end and an opposing distal end and a flange that radially outwardly projects from the proximal end of the body. A stopper is movably disposed with the compartment of the syringe barrel. A plunger rod includes a shaft having a proximal end and an opposing distal end and a plurality of teeth disposed on the shaft, the distal end of the shaft being secured to the stopper. A backstop engages the flange of the syringe barrel and at least a portion of the plurality of teeth of the plunger rod.
