KIM, Hyeon Jin,김현진,HONG, Seong Tshool,홍성출,YU, Jae Gak,유재각
申请号:
KRKR2016/012791
公开号:
WO2017/082611A1
申请日:
2016.11.08
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention relates to a strain having the ability to inhibit obesity and a pharmaceutical composition containing the same and, more specifically, to a strain having the ability to inhibit obesity by reducing the concentration of fatty acids dissolved in the gut fluid content, and to a pharmaceutical composition containing the same for the prevention or treatment of obesity or metabolic diseases caused by obesity. The intestinal strain having the ability to inhibit obesity by reducing the "concentration of fatty acids dissolved in the gut fluid content" in the mammalian gastrointestinal tract, according to the present invention, had no side effects in both animal experiments and clinical trials and showed a similar degree of obesity treatment effect to orlistat, which is a widely used representative anti-obesity drug. Therefore, the use of the intestinal strain having the ability to inhibit obesity by reducing the "concentration of fatty acids dissolved in the gut fluid content" in the mammalian gastrointestinal tract, according to the present invention, is expected to lead to a development as an anti-obesity drug that can be universally utilized by patients currently suffering from obesity, and thus to contribute greatly to human health.La présente invention concerne une souche ayant la capacité d'inhiber l'obésité et une composition pharmaceutique la contenant et, plus particulièrement, une souche ayant la capacité d'inhiber l'obésité en réduisant la concentration d'acides gras dissous dans le contenu de fluide intestinal, et une composition pharmaceutique la contenant pour la prévention ou le traitement d'obésité ou d'une maladie métabolique causée par l'obésité. La souche intestinale ayant la capacité d'inhiber l'obésité en réduisant la "concentration d'acides gras dissous dans le contenu de fluide intestinal" dans le tractus gastro-intestinal mammifère, selon la présente invention, n'avait pas d'effets secondaires lors d'essais cliniques et d'expérien