Recombinant rift valley fever virus encoding a dominant-negative inhibitor of DSRNA-dependent protein kinase in the NSS region

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专利权人:

The Board of Regents of the University of Texas System

发明人:

Tetsuro Ikegami,Birte Kalveram,Sabarish Indran,Olga Lihoradova,Alexander Freiberg

申请号：

US13766941

公开号：

US09144605B2

申请日:

2013.02.14

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Certain embodiments of the invention are directed to methods and compositions comprising a Rift Valley fever virus (RVFV) wherein a heterologous nucleic acid encoding a dsRNA-dependent protein kinase (PKR) inhibitor is inserted into the NSs region of the virus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/