A system and method include execution of a first nuclear imaging scan to acquire first nuclear imaging scan data of a body; generation of a target image based on the first nuclear imaging scan data execute a second nuclear imaging scan to acquire second nuclear imaging scan data of the body association of each of a plurality of portions of the second nuclear imaging scan data with a respective one of a plurality of motion phases of the body, generation, for each of the plurality of motion phases of the body, of a binned image based on the portion of the second nuclear imaging scan data associated with the motion phase, performance of motion-correction on each of the plurality of binned images based on the target image to generate a plurality of motion-corrected binned images, and generation of an image based on the target image and the plurality of motion-corrected binned images.