Matthew H. Katcher;Christopher J. Dinsmore;Alan B. Northrup
发明人:
Christopher J. Dinsmore,Matthew H. Katcher,Alan B. Northrup
申请号:
US12309149
公开号:
US08222269B2
申请日:
2007.07.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives of formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.