NBE-Therapeutics AG;The Scripps Research Institute
发明人:
Christoph Rader,Haiyong Peng,Roger Beerli,Lorenz Waldmeier,Ulf Grawunder
申请号:
US16040244
公开号:
US20180340026A1
申请日:
2018.07.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides antibodies, antibody drug conjugates, antibody-based fragments or antibody fragments (antigen-binding fragments), as well as antibody drug conjugates (ADCs) and chimeric antigen receptors (CARs), that specifically recognize human ROR1 and related compositions. Also provided in the invention are methods of using such antibodies in various diagnostic and therapeutic applications.