Horacio Uri Saragovi,Veronique Guillemard,Neil Cashman
申请号：
US14924388
公开号：
US20160130363A1
申请日:
2015.10.27
申请国别(地区):
US
年份:
2016
代理人:
摘要：
There are provided herein novel monoclonal antibodies that selectively bind and/or activate TrkC receptors, pharmaceutical compositions thereof and the use thereof for treating or preventing conditions which require activation of TrkC, such as amyotrophic lateral sclerosis and other neurodegenerative conditions and motor neuron diseases. The monoclonal antibodies are useful to screen for agents that share the same binding epitope on the TrkC receptor.
