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Use of an anti a synuclein antibody to diagnose an elevated level of a synuclein in the brain
专利权人:
发明人:
WEIHOFEN ANDREAS,ENGBER THOMAS,GRIMM JAN
申请号:
IN4233/DELNP/2014
公开号:
IN2014DN04233A
申请日:
2014.05.26
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
This disclosure relates to the use of anti-a-synuclein antibody to diagnose an elevated level of a-synuclein in the brain. Specifically, the disclosure relates to the method of assessing the levels of a-synuclein in a blood plasma or CSF following administration to the test subject of an anti-a-synuclein antibody or antigen-binding fragment thereof, which can bind a-synuclein with sufficient activity to alter the net efflux of a-synuclein from brain to blood, or from brain to CSF.
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