LIN, YUNG KAI,林咏凯,林詠凱,CHEN, KO HUA,陈克华,陳克華,KUAN, CHE YUNG,管哲雍,管哲雍
申请号:
TW099143031
公开号:
TWI413535B
申请日:
2010.12.09
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention relates to a co-polymer for tissue engineering, which comprises a polymer made by cross-linking hyaluronic acid and Pluronic F-127. The present invention also relates to a method of making a co-polymer of hyaluronic acid and Pluronic F-127, comprising cross-linking OH group on Pluronic F-127 structure with CH3, NH3, COOH or OH group on hyaluronic acid backbone by cross-linking agent.本發明係關於一種用於組織工程的共聚物,包含玻尿酸與Pluronic F-127交聯後之聚合物。本發明亦關於一種製備玻尿酸與Pluronic F-127共聚物的方法,包含使用交聯劑將Pluronic F-127結構上之OH基與玻尿酸骨架上一或多個選自由CH3、NH3、COOH及OH所組成群組之基團進行接合。