NOVEL 6-TRIAZOLOPYRIDAZINESULFANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AS MET INHIBITORS
Disclosed are benzimidazole and triazolopyridazinesulfanyl bezothiazole compounds represented by general formula (I). Examples of the compounds of formula (I) include methyl(6-{ [6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulphanyl} -1,3-banzothiazol-2-amine and 1-[2-(diethylamino)ethyl]-3-(6-{ [6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulphanyl} -1,3-benzothiazol-2-yl)urea. Also disclosed is the use of the compounds of formula (I) for treating blood vessel proliferation disorders, fibrotic disorders, `mesangial cell proliferation disorders, metabolic disorders, allergies, asthma, thrombosis, nervous system diseases, retinopathy, psoriasis, rheumatoid arthritis, diabetes, muscle degeneration and cancers.
