KUO, Gee-Hong,DEANGELIS, Alan,WANG, Aihua,Zhang, Yan,Emanuel,, Stuart L,Middleton, Steve A
申请号：
HUE10176670
公开号：
HUE029020T2
申请日:
2003.07.18
申请国别(地区):
HU
年份:
2017
代理人:
摘要：
The present invention provides substituted 1,3,5-triazine compounds of Formula (I): wherein X, Y and Z are independently selected from the group consisting of CH and N； wherein m is an integer from 2 to 5； wherein X, Y and Z include at least one CH atom and at least one N atom； and, wherein a N atom may simultaneously occupy only the X and Z positions； R 1 is selected from the group consisting of hydrogen and NH 2 ； and, R 2 is selected from the group consisting of phenyl (wherein phenyl is substituted with one substituent selected from the group consisting of halogen and heterocyclyl) and 1,4-benzodioxinyl； and pharmaceutically acceptable salts thereof as kinase inhibitors and a method for treating or ameliorating a kinase mediated disorder.
