ЯКОБС Антониус Арнольдус Кристиан (NL),ВЕРМЭЙ Пауль (NL),СЕГЕРС Рюид Филип Антон Мария (NL),ШРАЙЕР Карла Кристина (NL)
申请号：
RU2010146927/15
公开号：
RU2010146927A
申请日:
2009.04.16
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. The use of inorganic compositions containing carbohydrate, which is also found in live Lawsonia intracellularis cells in association with the outer cell membrane of these cells in the production of vaccines for protection against infection by Lawsonia intracellularis, wherein the vaccine is in a form suitable for systemic administration. ! 2. Use according to claim 1, characterized in that a composition comprising a carbohydrate, is a material derived from bacteria killed Lawsonia intracellularis. ! 3. Use according to claim 2, characterized in that a composition comprising a carbohydrate comprises whole cells of bacteria killed Lawsonia intracellularis. ! 4. Use according to any one of the preceding claims, characterized in that the vaccine comprises an adjuvant type "oil in water" comprising a submicron oil droplet. ! 5. Use according to claim 4, characterized in that the adjuvant comprises droplets of biodegradable oil and droplets of mineral oil, wherein the biodegradable oil droplets have an average size that differs from the average size of the droplets of mineral oil. ! 6. Use according to any one of claims 1-3 and 5, characterized in that the vaccine further comprises antigens of Mycoplasma hyopneumoniae and porcine circovirus. ! 7. Use according to claim. 4 characterized in that the vaccine further comprises antigens of Mycoplasma hyopneumoniae and porcine circovirus. ! 8. Inanimate composition comprising a carbohydrate that is also found in live Lawsonia intracellularis cells in association with the outer cell membrane of these cells, for the manufacture of a vaccine to protect against infection by Lawsonia intracellularis, wherein the vaccine is in a form suitable for systemic administration.1. Применение неживой композиции, содержащей углевод, который также обнаруживается в живых клетках Lawsonia intracellularis в ассоциации с наружной клеточной мембраной указанных клеток при производстве вакцины для защиты от инфекции, вызываемой Lawsonia intracellul
