Marc SCHILLER,Ulrich REINHOLD,Ulrike BERTRAM,Wolfgang PRANGE,Anika-Anina PHILIPP,Stefanie STRAUB,Annette GRAVE,Norbert POELLINGER
申请号:
US15990904
公开号:
US20180369151A1
申请日:
2018.05.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to an oral pharmaceutical dosage form comprising a plurality of coated particles, wherein said coated particles comprise a core which comprises a Tapentadol component and which is coated with a controlled release coating material, wherein the controlled release coating material comprises a lubricant component and a polymer component, wherein the polymer component comprises one or more cellulose ethers and/or one or more acrylates, and wherein the pharmaceutical dosage form provides controlled release of the Tapentadol component.