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カンデサルタン シレキセチル製剤
专利权人:
日本ケミファ株式会社
发明人:
望月 孝浩,柳本 剛,岡田 瑠生,林 和矢,牧野 良太,中島 康賀,矢澤 香織
申请号:
JP2017001556
公开号:
JP6346314B2
申请日:
2017.01.10
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide oral solid pharmaceutical compositions in which an additive selected from triethyl citrate, carnauba wax and sodium lauryl sulfate are compounded in a crystalline candesartan cilexetil or a salt thereof, and storage stability is improved.SOLUTION: The present invention relates to an oral solid pharmaceutical composition containing (1) crystalline candesartan cilexetil or a salt thereof, (2) an excipient, (3) a binder, (4) a lubricant, and (5) an additive selected from triethyl citrate, carnauba wax, and sodium lauryl sulfate and a method of producing the same. The tablet, the oral solid pharmaceutical composition in which an additive selected from triethyl citrate, carnauba wax and sodium lauryl sulfate are compounded in a crystalline candesartan cilexetil or a salt thereof has excellent storage stability compared with a tablet not containing triethyl citrate, carnauba wax, or sodium lauryl sulfate.SELECTED DRAWING: None
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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