Transdermal therapeutic system for the transdermal administration of buprenorphine, comprising a buprenorphine-containing self-adhesive layer structure, comprising A) a buprenorphine impermeable layer of reinforcement, and B) a pressure-sensitive adhesive layer, buprenorphine container, on said buprenorphine impermeable reinforcing layer, the adhesive layer a) comprising at least one polymeric pressure sensitive adhesive based on polysiloxanes or polyisobutylenes, b) an analgesically effective amount of buprenorphine base or a pharmaceutically acceptable salt thereof, c) a viscosity enhancing substance in an amount of 0.1% to 8% of said pressure sensitive adhesive layer, containing buprenorphine, and d) a carboxylic acid selected from the group consisting of oleic acid, linoleic acid, linolenic acid, levulinic acid and mixtures thereof, in an amount sufficient for dich The analgesically effective amount of buprenorphine is solubilized therein, in order to form a mixture that includes said viscosity enhancing substance, and wherein the carboxylic acid, buprenorphine and viscosity enhancing substance containing mixture forms dispersed deposits in said pressure sensitive adhesive, and wherein said pressure sensitive adhesive layer, containing buprenorphine, is the layer in contact with the skin.Sistema terapéutico transdérmico para la administración transdérmica de buprenorfina, que comprende una estructura de capas autoadhesiva contenedora de buprenorfina, que comprende A) una capa de refuerzo impermeable a la buprenorfina, y B) una capa de adhesivo sensible a la presión, contenedora de buprenorfina, sobre dicha capa de refuerzo impermeable a la buprenorfina, comprendiendo la capa adhesiva a) por lo menos un adhesivo sensible a la presión de base polimérica, basado en polisiloxanos o poliisobutilenos, b) una cantidad analgésicamente eficaz de base de buprenorfina o una sal farmacéuticamente aceptable de la misma, c) una sustancia potenciadora de la viscosidad en una c
