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crystalline material, pharmaceutical composition, and process for the preparation of a crystalline material
- 专利权人:
- BASF SE
- 发明人:
- Andreas Hafner,Beate Salvador,Eva RÖdel,Fritz Blatter,Marcus Vossen,Martin Szelagiewicz,Tiziana Chiodo,Tobias Hintermann
- 申请号：
- BR112015008552
- 公开号：
- BR112015008552A2
- 申请日:
- 2013.10.16
- 申请国别(地区):
- BR
- 年份:
- 2017
- 代理人:
- 摘要：
- 1/1 summary "crystalline material, pharmaceutical composition, and process for the preparation of a crystalline material" The present invention relates to crystalline materials comprising nilotinib and a carboxylic acid, Carboxylic acid ester, carboxylic acid amide or sulfonic acid as a cocrystal former, and pharmaceutical compositions comprising said materials. The invention also relates to processes for preparing said crystalline materials and methods of using such crystalline materials for the treatment of a disease condition in that tyrosine kinase inhibition is beneficial.1 / 1 resumo “material cristalino, composiã‡ãƒo farmacãšutica, e, processo para a preparaã‡ãƒo de um material cristalinoâ€� a presente invenã§ã£o refere-se a materiais cristalinos compreendendo nilotinibe e um ã¡cido carboxãlico, ã©ster de ã¡cido carboxãlico, amida de ã¡cido carboxãlico ou ã¡cido sulfã´nico como um formador de cocristal, e a composiã§ãµes farmacãªuticas que compreendem os referidos materiais. a invenã§ã£o tambã©m se refere a processos para preparar os referidos materiais cristalinos e a mã©todos de utilizaã§ã£o dessas matã©rias cristalinas para o tratamento de uma condiã§ã£o de doenã§a em que a inibiã§ã£o da tirosina quinase ã© benã©fica.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
