PATH;THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人:
Jonathan Lovell,Shuai Shao,Jumin Geng,Wei-Chiao Huang,Shwu-Maan Lee,Charles Richter King
申请号：
US16399581
公开号：
US20190255188A1
申请日:
2019.04.30
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present disclosure provides nanostructures (e.g., monolayer or bilayer nanostructures) comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within monolayer or bilayer in the porphyrin macrocycle. The nanostructures can have presentation molecules comprising epitopes from microorganisms with a histidine tag attached thereto, such that at least a part of the his-tag is within the monolayer or bilayer and coordinated to the cobalt metal core and the presentation molecules are exposed to the outside of the nanostructures. The nanostructures can further comprise a cargo. The nanostructures can be used to deliver the cargo to an individual.
