JULIUS W.J. DICKENS,IOANNES NICOLAOS HOUPIS,YOLANDE LYDIA LANG,CARINA LEYS,SIGRID CARL MARIA STOKBROEKX,JOHAN ERWIN EDMOND WEERTS
申请号:
BRPI0811859
公开号:
BRPI0811859A2
申请日:
2008.05.13
申请国别(地区):
BR
年份:
2014
代理人:
摘要:
This invention provides novel crystalline forms of mono-HCl salts and a mono-HCl salt hydrate of JNJ-26481585, an inhibitor of histone deacetylases. The invention also relates to processes for production of these forms, to intermediates used in these processes, to pharmaceutical compositions comprising these forms, and to the use of these forms in medical treatment for instance as a medicine to inhibit proliferative conditions, such as cancer and leukemia.