The present invention relates to a combination comprising (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, or a pharmaceutically acceptable salt thereof, hereafter "Compound(I)", and a taxane. Taxanes include established cancer drugs such as docetaxel (Taxotere™) and paclitaxel (Taxol™). Such combinations may be useful in the treatment or prophylaxis of cancer. The invention also relates to a pharmaceutical composition comprising such Compound(I)and a taxane. The invention further relates to a method of treatment comprising the simultaneous, sequential or separate administration of Compound(I)and a taxane, to warm-blooded animal, such as man. The invention also relates to a kit comprising Compound(I)and a taxane, optionally with instructions for use.
