BALDINO, CARMEN M.,CASERTA, JUSTIN L.,LEE, CHEE-SENG,DUMAS, STEPHANE A.,FLANDERS, YVONNE L.
申请号：
PL12780393
公开号：
PL2776432T3
申请日:
2012.10.24
申请国别(地区):
PL
年份:
2017
代理人:
摘要：
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of CK1, CK1&gamma；1, CK1&gamma；2, CK1&gamma；3, CK2, Pim 1, Pim2, Pim3, the TGF&bgr； pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of CK1, CK1&gamma；1, CK1&gamma；2, CK1&gamma；3, CK2, Pim 1, Pim2, Pim3, the TGF&bgr； pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway.
