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Ophthalmic Pharmaceutical composition, antimicrobial compounds based carbolina
专利权人:
ALCON RESEARCH; LTD.
发明人:
申请号:
ARP120104126
公开号:
AR088639A1
申请日:
2012.11.02
申请国别(地区):
AR
年份:
2014
代理人:
摘要:
Includes anthrax compounds used to treat infections, such as viral conjunctivitis. Treatment for other infections, including eye infections. More specifically, compounds including anthrax compounds for the treatment of eye infections, such as viral conjunctivitis, in particular conjunctivitis caused by glands. Claim 1: an ophthalmic drug ingredient for the treatment of ocular infection, including an effective amount of a formula (1) or a salt acceptable for the drug, wherein X = C or N; and 8345 = combine,CH8322;it is life.C (O) O C (O) NR o SON = 0 or 1; P = 0, 1 or 2; R 1 = h, halogen, asphalt, nitro or amide; R 2 = h or asphalt; R3 and r83088 were selected from h, asphalt, cyclopropyl, isotar, isocyclopentadiene, arilo or isopropyl respectively; O r 3 and r83088 can form a cyclopentadiene or non cyclopentadiene ring, which is composed of 3 to 6 optional members and replaced by tar or halogen; r83099 = r8311; n (r831222) r8313;R8311; (C (o) n (r83212) r8313 or r8311;; so8322; r183044;R83100a = h or tar; r8311a = zero or optional alternative tar; r831222 and r831393 are selected from h, tar, ISO tar, cyclopentadiene, ISO cyclopropene, arilo or ISO propene respectively, each of which can be alternatively replaced, O r831222 can be combined with r8311y / or r8313 to form a variant consisting of 3 to 8 optional members, replaced by halogen, asphalt, cyanogen, nr1830404;y 2Fo S (O)And r830404 = h or rental. 3. Claim 3: the composition of claim 1, wherein, in addition to a formula compound, it also includes an anti infective or anti-inflammatory preparation (1). 13. Claim 4: composition of claim 3, in which antiinfective or anti-inflammatory agents are selected from the following categories: steroid anti-inflammatory agents, non steroid anti-inflammatory agents, nepafenac, dexamethana and combinations of these agents. Requirement 11: ophthalmic drug ingredients for the treatment of eye infections,comprising an effective amount of a compound according to formula (2) or a
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