A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing (821) and a first fluid passageway (111) extending from the module housing. The first fluid passageway has a patient end (120) remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator (332) is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell (903,2464) is configured to hold at least a portion of the first component.
