GLYCOANTICORPS ANTI-THF-ALPHA ET LEURS UTILISATIONS

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专利权人:

ACADEMIA SINICA

发明人:

WONG, CHI-HUEY,WU, CHUNG-YI

申请号：

CA2950433

公开号：

CA2950433A1

申请日:

2015.05.27

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present disclosure relates to a novel class of anti-TNFa monoclonal antibodies or antigen binding fragments comprising a homogeneous population of anti-TNFa IgG molecules having the same N-glycan on each of Fc. The antibodies of the invention can be produced from anti-TNFa monoclonal antibodies by Fc glycoengineering. The glycoantibodies of the invention may have improved therapeutic values compared to the corresponding monoclonal antibodies that have not been glycoengineered.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/