EINSELE, HERMANN,HUDECEK, MICHAEL,LETSCHERT, SEBASTIAN,NERRETER, THOMAS,SAUER, MARKUS
申请号：
CA3082334
公开号：
CA3082334A1
申请日:
2018.11.20
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention generally relates to immunotherapy with chimeric antigen receptor (CAR}- engineered T-cells. In particular, the invention relates immunotherapy with chimeric antigen receptor (CAR)-engineered T-cells to target sub-populations of cancer cells that are characterized by low expression of a cancer cell surface antigen, more particular the invention relates to immunotherapy with chimeric antigen receptor (CAR)-engineered T-cells targeting CD19 (CD19CART) in multiple myeloma, a clonal proliferation of plasma cells.
