NEW, THE MIGRATION OF DENDRITIC CELL-INDUCING POLYPEPTIDES, AND MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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专利权人:

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);UNIVERSITE CLAUDE BERNARD - LYON 1

发明人:

PERSAT, FLORENCE,VINCENT, CLAUDE,CESBRON-DELAUW, MARIE-FRANCE

申请号：

AT07731380

公开号：

AT544779T

申请日:

2007.04.27

申请国别(地区):

AT

年份:

2012

代理人:

摘要：

The invention concerns a polypeptide corresponding to amino acids 26 to 75 of the sequence of GRA5-RH protein of SEQ ID No 1: MASVKRVWAVMIVNVLALIFVGVAGSTRDVGSGGDDSEGARGRE QQQVQQHEQNEDRSLFERGRAAVT-GHPVRTAVGLAAAWAWSLL RLLKRRRRRAIQEESKESATAEEEEVAEEE, its variants acting on dendritic cell migration, homologues acting on dendritic cell migration, and fragments thereof acting on dendritic cell migration, as well as the pharmaceutical compositions thereof comprising such polypeptides and their use for making a medicine for preventing or treating skin and mucous membrane conditions involving dendritic cells or Langerhans cells.

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