Amato J. Giaccia,Erinn Bruno Rankin,Jennifer R. Cochran,Douglas Jones,Mihalis Kariolis,Katherine Fuh,Yu Miao,Susan Hershenson
申请号:
US14650854
公开号:
US09822347B2
申请日:
2013.12.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL, MER or Tyro3 protein activity, for example by competitive or non-competitive inhibition of the binding interaction between AXL, MER or Tyro3 and its ligand GAS6.