Christine Klaus,Maria Alejandra Raimondi,Scott Richard Daigle,Roy MacFarlane Pollock,Vivek Chopra
申请号:
US15547427
公开号:
US20180028552A1
申请日:
2016.02.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure relates to a combination of an inhibitor of human histone methyltransferase DOT1L, such as EPZ-5676 or salts thereof, and one or more DNMT inhibitors, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.