The present invention relates to antimicrobial compositions comprising at least one antimicrobial azole compound, particularly imidazole, triazole or thiazole compounds, and at least one polymeric biguanide compound. Methods for their use in treating or preventing microbial infections of the skin and epithelial lined body cavities, such as ears, using the compositions of the invention are also described.本發明係關於抗微生物組合物，其包含至少一種抗微生物唑類化合物，特定言之咪唑、三唑或噻唑化合物，及至少一種聚合雙胍化合物。亦闡述使用本發明該等組合物治療或預防皮膚及內襯上皮體腔(諸如：耳)之微生物感染之方法。
